CUET UG Biology Booster Test 2 Infertility and ART Techniques
📌 Answers are locked once submitted — results and explanations appear at the end.
QUESTION 1 OF 20
Why do sexually transmitted infections often remain undetected for a long time in females, leading to PID?
QUESTION 2 OF 20
Which condition is NOT listed as a potential long-term complication of untreated STIs?
QUESTION 3 OF 20
Match the cause of infertility with the clinical approach:
| List I | List II |
|---|---|
| 1. Correctable disorder | a. ART techniques |
| 2. Non-correctable disorder | b. Infertility clinics |
| 3. Congenital factor | c. Diagnosis and treatment |
| 4. Psychological factor | d. Specialised healthcare units |
QUESTION 4 OF 20
Why is it incorrect to solely blame the female for a couple being childless in the Indian context?
QUESTION 5 OF 20
Regarding the "test tube baby" program:
I. Ova and sperms are induced to form a zygote in a laboratory.
II. Fertilisation occurs within the female's body (in-vivo).
QUESTION 6 OF 20
Embryos formed by in-vivo fertilisation can be used for transfer to assist females who:
QUESTION 7 OF 20
Arrange the following based on the timeline of ZIFT:
1.Zygote formation in laboratory
1. Embryo reaches up to 8 blastomeres
1. Transfer into fallopian tube
QUESTION 8 OF 20
Why is the zygote transferred to the fallopian tube in ZIFT rather than the uterus?
QUESTION 9 OF 20
Arrange the stages for Intra Uterine Transfer:
1. Fertilisation in laboratory
2. Development beyond 8 blastomeres
3. Transfer into the uterus
QUESTION 10 OF 20
Match the ART procedure with its specific transfer site:
| List I | List II |
|---|---|
| 1. ZIFT | a. Uterus |
| 2. IUT | b. Fallopian tube |
| 3. GIFT | c. Fallopian tube |
| 4. AI | d. Vagina/Uterus |
QUESTION 11 OF 20
For which specific type of female is the GIFT technique most applicable?
QUESTION 12 OF 20
Which of the following is NOT required for a successful GIFT procedure?
QUESTION 13 OF 20
Regarding ICSI and IVF:
I. Both can involve forming an embryo in a laboratory.
II. ICSI requires a sperm to be directly injected into the ovum.
QUESTION 14 OF 20
ICSI is considered a "specialised procedure" because it involves:
QUESTION 15 OF 20
Arrange the factors in a case of AI:
1. Identification of low sperm count in male
1. Semen collection from healthy donor
1. Artificial introduction into the female
QUESTION 16 OF 20
Artificial insemination is NOT typically chosen if the primary problem is:
QUESTION 17 OF 20
In comparison to vaginal insemination, IUI does NOT:
QUESTION 18 OF 20
Intra-uterine insemination (IUI) is a specific form of:
QUESTION 19 OF 20
QUESTION 20 OF 20
Test Complete!
Answer Review
1 Why do sexually transmitted infections often remain undetected for a long time in females, leading to PID?
Many STIs (e.g., Chlamydia, Gonorrhe A) cause mild or no noticeable symptoms in the early stages in females. Because symptoms are absent or minor, individuals do not seek medical attention. This lack of treatment allows the infection to ascend from the vagina to the upper reproductive tract, causing Pelvic Inflammatory Disease (PI D).
The correct answer is ( C). In the context of reproductive health, many STIs are termed "silent" because they do not manifest acute clinical symptoms in women until complications like PID arise. PID occurs when the infection spreads to the uterus, fallopian tubes, and ovaries. Because the patient is asymptomatic, the infection remains untreated, leading to permanent damage such as scarring of the fallopian tubes.
- Option A → If symptoms were severe, patients would seek immediate treatment, preventing long-term complications.
- Option B → This is factually incorrect; a hallmark of many STIs is their asymptomatic nature, especially in women.
- Option D → Social stigma is often high, which further discourages testing, but it is not the biological reason for the infection being "undetected" at a physiological level.
Used: Elimination
Application: By recognizing the biological reality that asymptomatic infections are a clinical challenge, we can rule out the options suggesting severe symptoms or universal presentation.
Final Logic: Asymptomatic nature is the primary reason for delayed diagnosis of STIs in females.
"Silent STIs = Silent Damage."
2 Which condition is NOT listed as a potential long-term complication of untreated STIs?
Untreated STIs lead to severe reproductive damage. Documented complications include PID, abortions, stillbirths, ectopic pregnancies, and cancer. Spontaneous twin pregnancies are a biological occurrence, not a pathological complication of STIs.
The correct answer is ( C). Untreated STIs (like Syphilis or Gonorrhe A) can cause irreparable damage to the reproductive system. However, they do not cause "spontaneous twin pregnancies." Twins result from either the release of two ova (dizygoti C) or the splitting of one zygote (monozygoti C), which is independent of STI infection status.
- Option A → Untreated chronic infections can lead to tissue dysplasia and eventual cancer of the reproductive tract.
- Option B → STIs can cause placental infections, leading to stillbirths.
- Option D → PID is one of the most common and direct complications of untreated ascending STIs.
Used: Fact Checking
Application: Identify the "odd one out" by distinguishing between pathological complications and natural biological variations.
Final Logic: Twin pregnancy is a natural reproductive outcome, not a disease complication.
"STI Complications: PID, Cancer, Stillbirth, Ectopic, Infertility." (Remember PSC EI).
3 Match the cause of infertility with the clinical approach:
| List I | List II |
|---|---|
| 1. Correctable disorder | a. ART techniques |
| 2. Non-correctable disorder | b. Infertility clinics |
| 3. Congenital factor | c. Diagnosis and treatment |
| 4. Psychological factor | d. Specialised healthcare units |
Correctable disorders are addressed via diagnosis and treatment. Non-correctable issues require ART. Congenital factors are evaluated in infertility clinics. Psychological factors require specialized counseling/healthcare units.
The correct answer is ( A). 1-iii: Disorders that can be corrected are handled by specific diagnosis and medical treatment. 2-i: In cases where the condition is non-correctable, Assisted Reproductive Technologies (ART) are employed. 3-ii: Infertility clinics provide the infrastructure to diagnose congenital (present from birth) structural defects. 4-iv: Psychological infertility (stress, anxiety affecting fertility) is managed by specialized healthcare/counseling units.
- Option B, C, D → These do not align with the logical flow of medical triage in reproductive health services.
Used: Option Grouping
Application: Link the severity of the cause with the intensity of the intervention.
Final Logic: Logical pairing of clinical severity to the corresponding medical intervention.
"Correct-Treat, Non-correct-ART."
4 Why is it incorrect to solely blame the female for a couple being childless in the Indian context?
Infertility is a joint responsibility. Studies show that male-factor infertility is as common, if not more common, than female-factor. Cultural bias often unfairly blames the woman.
The correct answer is ( B). In many societies, including the Indian context, women are often incorrectly blamed for infertility. However, medical statistics show that infertility can be caused by physical, congenital, immunological, or psychological factors in either the male or the female. Therefore, it is clinically inaccurate and socially unjust to attribute the cause solely to the female.
- Option A → Females can certainly have factors contributing to infertility (e.g., ovulatory issues).
- Option C → Infertility is a physical/biological condition, not "only" psychological.
- Option D → Physical factors are present in both genders.
Used: Contextual/Tonal Matching
Application: Understanding the socio-medical stance provided in the curriculum regarding gender equality in infertility.
Final Logic: Infertility is a couple-based issue with equal contribution possibilities.
"It takes two to tango; it takes two to diagnose."
5 Regarding the "test tube baby" program:
I. Ova and sperms are induced to form a zygote in a laboratory.
II. Fertilisation occurs within the female's body (in-vivo).
Test tube baby (IVF) involves in-vitro (outside body) fertilization. Statement I is the definition of IVF. Statement II is the definition of in-vivo, which is the opposite of IVF.
The correct answer is (A). "Test tube baby" refers to In-Vitro Fertilisation (IVF), where fertilisation takes place outside the female body under simulated conditions. Statement II suggests in-vivo (within the body) fertilisation, which contradicts the core principle of the IVF technique.
- Option B → Reverses the truth value of the statements.
- Option C → Incorrect because Statement II describes natural/in-vivo fertilisation.
- Option D → Incorrect because Statement I correctly describes the lab-based zygote formation.
Used: Substitution
Application: Substitute "In-Vitro" for "outside" and "In-Vivo" for "inside" to verify the statements.
Final Logic: IVF = In Vitro (outside), therefore statement II is false.
"In-Vitro = Glass (Test tube), In-Vivo = Life (Body)."
6 Embryos formed by in-vivo fertilisation can be used for transfer to assist females who:
ART is specifically for couples who cannot conceive through natural intercourse. The goal is to overcome physiological barriers to pregnancy.
The correct answer is ( B). The entire purpose of Assisted Reproductive Technology (ART) is to provide a solution for couples who are infertile and cannot conceive through natural intercourse. While ( A) might be true for some procedures, the overarching reason for seeking any ART intervention is the inability to conceive normally.
- Option A → Not always true; some donors provide ova for those who cannot produce them.
- Option C → High sperm count is not a cause for requiring ART.
- Option D → ART requires simulated conditions (especially IVF); this is a contradictory statement.
Used: Elimination
Application: Eliminate options that describe healthy, fertile conditions or contradictory lab requirements.
Final Logic: ART exists because of the inability to conceive naturally.
"ART = Assisting Reproductive Troubles."
7 Arrange the following based on the timeline of ZIFT:
1.Zygote formation in laboratory
1. Embryo reaches up to 8 blastomeres
1. Transfer into fallopian tube
Step 1: Fertilization occurs to form the Zygote. Step 2: The zygote undergoes cleavage (early embryo stage) up to 8 cells. Step 3: This stage is transferred into the fallopian tube.
The correct answer is ( A). Zygote Intra-Fallopian Transfer (ZIFT) involves fertilisation in the lab, followed by culture until the embryo reaches the 8-cell (blastomere) stage. Once it reaches this stage, it is surgically transferred into the fallopian tube for natural implantation to continue.
- Options B, C, D → These scramble the biological sequence of development and clinical intervention.
Used: Contextual/Tonal Matching
Application: Follow the chronological growth of the embryo in the laboratory setting.
Final Logic: Fertilization leads to cleavage, followed by implantation.
"Fertilise → Transfer → Cleavage."
8 Why is the zygote transferred to the fallopian tube in ZIFT rather than the uterus?
ZIFT is specific to the "Zygote" or "Early Embryo" stage (up to 8 cells). In a natural pregnancy, the embryo travels through the fallopian tube to the uterus. ZIFT mimics this natural journey.
The correct answer is ( B). In natural conception, the zygote travels down the fallopian tube toward the uterus. By transferring an embryo with 8 or fewer blastomeres directly into the fallopian tube, the procedure allows the embryo to complete its natural transit and implantation process, thereby increasing the chances of successful pregnancy.
- Option A → If it had more than 8 blastomeres, it would be an IUT procedure, not ZIFT.
- Option C → The uterus is the natural place for implantation, but early embryos require the fallopian tube environment first.
- Option D → Simulated conditions are used in the lab; the transfer is just the final step.
Used: Elimination
Application: Differentiate ZIFT (fallopian) from IUT (uterine) based on embryo development stage.
Final Logic: ZIFT = Fallopian = up to 8 cells.
"ZIFT = Z for Zygote, F for Fallopian."
9 Arrange the stages for Intra Uterine Transfer:
1. Fertilisation in laboratory
2. Development beyond 8 blastomeres
3. Transfer into the uterus
The sequence begins with development beyond 8 blastomeres. This is followed by fertilisation in the laboratory. Finally, the embryo is transferred into the uterus.
According to the given sequence: (2) Development beyond 8 blastomeres is placed first. (1) Fertilisation in the laboratory follows. (3) The embryo is then transferred into the uterus. Thus, the sequence 2 → 1 → 3 matches Option B.
- Option A follows a different order and does not match the required sequence.
- Option C begins with uterine transfer instead of the specified first step.
- Option D transfers the embryo before the required sequence is completed.
Used: Sequence Matching
Application:
- Compare each option with the required sequence and identify the one that reproduces it exactly.
Final Logic:
- Only Option B matches 2 → 1 → 3.
>8 Cells → Fertilisation → Uterus
10 Match the ART procedure with its specific transfer site:
| List I | List II |
|---|---|
| 1. ZIFT | a. Uterus |
| 2. IUT | b. Fallopian tube |
| 3. GIFT | c. Fallopian tube |
| 4. AI | d. Vagina/Uterus |
ZIFT: Zygote to Fallopian Tube. IUT: Embryo to Uterus. GIFT: Gametes to Fallopian Tube. AI: Semen to Vagina/Uterus.
The correct answer is ( A). This is a foundational matching of ART acronyms to their anatomical targets. 1-ii: ZIFT transfers the zygote to the fallopian tube. 2-i: IUT transfers the embryo to the uterus. 3-iii: GIFT transfers gametes to the fallopian tube. 4-iv: Artificial Insemination (AI) introduces semen into the female reproductive tract (vagina or uterus).
- Options B, C, D → Mismatched anatomical sites for the specific ART procedures.
Used: Substitution
Application: Expand the acronyms to their definitions to verify the location.
Final Logic: Accurate mapping of anatomical sites to reproductive procedures.
"ZIFT/GIFT = Fallopian Tube; IUT = Uterus."
11 For which specific type of female is the GIFT technique most applicable?
GIFT (Gamete Intra-Fallopian Transfer) transfers donor ova into the fallopian tube of a recipient. This is designed for females who are unable to produce their own ova but whose reproductive tract can support the subsequent stages of pregnancy.
The correct answer is ( B). GIFT stands for Gamete Intra-Fallopian Transfer. It involves the transfer of an ovum collected from a donor into the fallopian tube of another female who cannot produce one but can provide a suitable environment for fertilisation and further development.
- Option A → If a female cannot provide a suitable environment for fertilisation, GIFT will not work because it relies on natural internal fertilisation.
- Option C → A uterus is required for the development of the fetus; this option describes a condition where even IVF or GIFT would not lead to a full-term pregnancy.
- Option D → Producing too many ova is not the criteria for needing an ovum donor; usually, stimulation protocols are adjusted for such cases.
Used: Elimination
Application: Eliminate based on the definition of GIFT (donor ovum + recipient environment).
Final Logic: GIFT requires a functional internal environment for the gametes to fertilize and develop.
A) go to Fallopian Tube."
12 Which of the following is NOT required for a successful GIFT procedure?
GIFT allows fertilisation to occur inside the fallopian tube. Direct injection of sperm (ICSI) is a separate, more advanced laboratory technique.
The correct answer is ( C). In GIFT, the ova and sperms are transferred into the fallopian tube, where fertilisation occurs naturally within the female body. Direct injection of sperm into the ovum is the definition of ICSI (Intra-cytoplasmic Sperm Injection), not GIFT.
- Option A → A donor ovum is necessary if the female cannot produce her own.
- Option B → The recipient's body must be capable of supporting the pregnancy.
- Option D → The transfer of the ovum is the primary step of the GIFT technique.
Used: Odd One Out
Application: Identify the procedure that involves laboratory manipulation of the egg vs. natural fertilisation.
Final Logic: GIFT = Natural fertilisation; ICSI = Lab-assisted fertilisation.
"GIFT = Natural fertilization; ICSI = Artificial injection."
13 Regarding ICSI and IVF:
I. Both can involve forming an embryo in a laboratory.
II. ICSI requires a sperm to be directly injected into the ovum.
Both are ART procedures conducted in a laboratory. ICSI is a specific type of IVF procedure that uses mechanical injection.
The correct answer is ( C). Both IVF and ICSI are Assisted Reproductive Technologies conducted outside the body to form an embryo (Statement I). ICSI is a specialized procedure under the umbrella of IVF where a sperm is injected directly into the ovum to facilitate fertilisation, especially in cases of male infertility (Statement II).
- Options A, B, D → These are incorrect because both statements accurately describe the relationship between IVF and ICSI.
Used: Substitution
Application: Verify the definitions of ICSI and IVF.
Final Logic: ICSI is a subtype of laboratory-based fertilisation (IVF).
"ICSI = Injection into Cytoplasm."
14 ICSI is considered a "specialised procedure" because it involves:
ICSI stands for Intra-cytoplasmic Sperm Injection. It requires micro-manipulation tools to inject a single sperm into an egg.
The correct answer is ( B). ICSI is "specialised" because it goes beyond standard IVF (where sperm and egg are placed together in a dish). It requires sophisticated equipment to physically insert one selected sperm directly into the cytoplasm of the egg, overcoming severe male infertility.
- Option A → Natural mating does not happen in clinics.
- Option C → This is Artificial Insemination (AI).
- Option D → This describes IUT, not ICSI.
Used: Contextual/Tonal Matching
Application: Associate "specialised" with high-tech micro-manipulation.
Final Logic: ICSI = Direct micro-injection.
"I for Injection, C for Cytoplasm."
15 Arrange the factors in a case of AI:
1. Identification of low sperm count in male
1. Semen collection from healthy donor
1. Artificial introduction into the female
Step 1: Diagnose the problem (low sperm count). Step 2: Collect semen from a donor to bypass the male partner. Step 3: Introduce the semen into the female reproductive tract.
The correct answer is ( A). AI (Artificial Insemination) is indicated when the husband cannot inseminate or has low sperm counts (Step 1). A donor's semen is then collected (Step 2) and artificially introduced into the wife's vagina or uterus (Step 3).
- Options B, C, D → Incorrect sequence of clinical diagnosis and procedure.
Used: Contextual/Tonal Matching
Application: Follow the logical medical workflow: Diagnosis -> Solution -> Procedure.
Final Logic: Diagnosis leads to the selection of the donor, followed by the actual procedure.
"AI = Diagnose, Collect, Inject."
16 Artificial insemination is NOT typically chosen if the primary problem is:
AI addresses male fertility issues. If the female cannot produce an ovum, AI will not resolve the issue, as sperm introduction requires an egg for fertilization.
The correct answer is ( C). Artificial Insemination focuses on delivering healthy sperm to the female reproductive tract. If the female herself cannot produce an ovum, AI alone will not lead to pregnancy; techniques like GIFT or IVF with a donor ovum would be required instead.
- Option A, B, D → These are the primary indications for choosing AI.
Used: Elimination
Application: Eliminate conditions that AI is specifically designed to treat.
Final Logic: AI is a male-focused solution (delivering sperm).
"AI targets the Sperm, not the Egg."
17 In comparison to vaginal insemination, IUI does NOT:
IUI stands for Intra-uterine Insemination. It is about sperm delivery, not embryo transfer (which is ZIFT or IUT).
The correct answer is ( C). IUI involves placing processed sperm directly into the uterus. It is not an embryo transfer procedure, which involves placing a fertilized embryo (like in ZIFT or IUT) into the reproductive tract.
- Option A → This is exactly what IUI does.
- Option B → IUI often uses donor semen if the male partner's sperm count is critically low.
- Option D → IUI is a primary technique to help correct/circumvent low sperm count issues.
Used: Elimination
Application: Distinguish between insemination (sperm) and embryo transfer (fertilized egg).
Final Logic: IUI delivers sperm; embryo transfer is a different category.
"IUI = Sperm into Uterus, not Embryo."
18 Intra-uterine insemination (IUI) is a specific form of:
IUI is a clinical sub-method of AI where sperm is washed and placed into the uterus.
The correct answer is ( B). Intra-Uterine Insemination is a technique used to artificially deposit sperm into the female's uterus, bypassing the vagina, to increase the likelihood of fertilisation. It is classified under the broad category of Artificial Insemination (AI).
- Option A → Fertilisation is not external in IUI.
- Option C & D → These involve embryos or zygotes, whereas IUI involves sperm only.
Used: Definition Matching
Application: Categorize IUI under the umbrella of AI.
Final Logic: IUI = A type of AI.
"IUI is a smarter version of AI."
19
The passage lists long-term effects: PID, abortion, stillbirth, infertility, and cancer. These impact not just individuals, but the overall reproductive health of society.
The correct answer is ( B). As explicitly stated in the passage, STIs are a threat because they cause severe, lasting damage such as PID, ectopic pregnancies, infertility, and reproductive tract cancer, which have long-term consequences for the health and well-being of the population.
- Option A → STIs are not usually immediately fatal.
- Option C → While they affect fertility, the "threat" described in the text centers on complications (PID, Cancer), not broad population demographics.
- Option D → STIs affect all age groups, particularly the sexually active population.
Used: Contextual/Tonal Matching
Application: Direct reference to the passage provided.
Final Logic: Passage identifies complications as the threat.
"STI = Serious, Total, Impact."
20
"Ectopic" literally means out of place. The passage lists this as a specific complication.
The correct answer is ( B). An ectopic pregnancy is defined as a pregnancy where the fertilized egg implants outside the uterus, most commonly in the fallopian tubes. This is listed in the passage as a complication of STIs.
- Option A → A stillbirth is a birth after 20 weeks gestation where the fetus shows no signs of life, but it happens in the uterus.
- Option C → PID is inflammation of the pelvic organs.
- Option D → Infertility is the inability to conceive.
Used: Definition Matching
Application: Use medical terminology knowledge regarding "ectopic."
Final Logic: Ectopic = Outside the uterus.
"Ectopic = Exit-topic (Outside)."
